| Secretary of State | John Quincy Adams, 1817 |
| Secretary of the Treasury | William H. Crawford (Cont.) |
| Secretary of War | John C. Calhoun, 1817 |
| Attorney General | Richard Rush (Cont.) William Wirt, 1817 |
| Secretary of the Navy | B. W. Crowninshield (Cont.) Smith Thompson, 1818 Samuel L. Southard, 1823 |