| Secretary of State | James G. Blaine, 1881 |
| Secretary of the Treasury | William Windom, 1881 |
| Secretary of War | Robert T. Lincoln, 1881 |
| Attorney General | Wayne MacVeagh, 1881 |
| Postmaster General | Thomas L. James, 1881 |
| Secretary of the Navy | William H. Hunt, 1881 |
| Secretary of the Interior | Samuel J. Kirkwood, 1881 |