| Secretary of State | James G. Blaine, 1889 John W. Foster, 1892 |
| Secretary of the Treasury | William Windom, 1889 Charles Foster, 1891 |
| Secretary of War | Redfield Proctor, 1889 Stephen B. Elkins, 1891 |
| Attorney General | William H. H. Miller, 1889 |
| Postmaster General | John Wanamaker, 1889 |
| Secretary of the Navy | Benjamin F. Tracy, 1889 |
| Secretary of the Interior | John W. Noble, 1889 |
| Secretary of Agriculture | Jeremiah M. Rusk, 1889 |