| Secretary of State | James G. Blaine (Cont.) F. T. Frelinghuysen, 1881 |
| Secretary of the Treasury | William Windom (Cont.) Charles J. Folger, 1881 Walter Q. Gresham, 1884 Hugh McCulloch, 1884 |
| Secretary of War | Robert T. Lincoln (Cont.) |
| Attorney General | Wayne MacVeagh (Cont.) Benjamin H. Brewster, 1881 |
| Postmaster General | Thomas L. James (Cont.) Timothy O. Howe, 1881 Walter Q. Gresham, 1883 Frank Hatton, 1884 |
| Secretary of the Navy | William H. Hunt (Cont.) William E. Chandler, 1882 |
| Secretary of the Interior | Samuel J. Kirkwood (Cont.) Henry M. Teller, 1882 |